BDBM50157844 3-Hydroxy-5-methyl-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::CHEMBL181709

SMILES: Cc1csc2n(Cc3ccccc3)c(=O)n(O)c(=O)c12

InChI Key: InChIKey=TWKGDKPYCBTGHU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA excision repair protein ERCC-5 (Homo sapiens (Human))	BDBM50157844 (3-Hydroxy-5-methyl-1-phenyl-1H-thieno[2,3-d]pyrimi...) Show SMILES Cc1csc2n(Cc3ccccc3)c(=O)n(O)c(=O)c12 Show InChI InChI=1S/C14H12N2O3S/c1-9-8-20-13-11(9)12(17)16(19)14(18)15(13)7-10-5-3-2-4-6-10/h2-6,8,19H,7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.99	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the xeroderma pigmentosum G				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM50157844 (3-Hydroxy-5-methyl-1-phenyl-1H-thieno[2,3-d]pyrimi...) Show SMILES Cc1csc2n(Cc3ccccc3)c(=O)n(O)c(=O)c12 Show InChI InChI=1S/C14H12N2O3S/c1-9-8-20-13-11(9)12(17)16(19)14(18)15(13)7-10-5-3-2-4-6-10/h2-6,8,19H,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0280	n/a	n/a	n/a	n/a	n/a	n/a
Athersys, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against the Flap endonuclease-1				Bioorg Med Chem Lett 15: 277-81 (2004) Article DOI: 10.1016/j.bmcl.2004.10.086 BindingDB Entry DOI: 10.7270/Q2HD7V46
					More data for this Ligand-Target Pair