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BDBM50157875 CHEMBL3786776

SMILES: CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1

InChI Key: InChIKey=MYJGHGXHMIXENY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157875   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Cavia porcellus (Guinea pig))
BDBM50157875
PNG
(CHEMBL3786776)
Show SMILES CC1CCN(CCCOc2nc(nc3CCCCc23)-c2ccccc2)CC1
Show InChI InChI=1S/C23H31N3O/c1-18-12-15-26(16-13-18)14-7-17-27-23-20-10-5-6-11-21(20)24-22(25-23)19-8-3-2-4-9-19/h2-4,8-9,18H,5-7,10-17H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
26n/an/an/an/an/an/an/an/a



Renmin Hospital of Wuhan University

Curated by ChEMBL


Assay Description
Tested for functional activity against neuronal nicotinic acetylcholine receptor(nAChR) expressed in K177 cells using isotopic rubidium efflux assay.


Bioorg Med Chem Lett 26: 2051-6 (2016)


BindingDB Entry DOI: 10.7270/Q25Q4XZN
More data for this
Ligand-Target Pair