BDBM50157912 13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,19-tetramethyl-5,9,18-trioxapentacyclo[14.2.1.01,14.04,13.06,11]nonadeca-6(11),7-diene-10,15,17-trione::CHEMBL183507
SMILES: COc1ccc(cc1)-c1cc2O[C@]3(C)CC[C@]45OC(=O)[C@](OC)(C(=O)[C@]4(C)[C@]3(O)Cc2c(=O)o1)C5(C)C
InChI Key: InChIKey=AOFMVUCAUSHJLI-RKFAPSRVSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterases (Homo sapiens (Human)) | BDBM50157912 (13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibitory concentration against Butyrylcholinesterase activity | Bioorg Med Chem Lett 15: 353-6 (2004) Article DOI: 10.1016/j.bmcl.2004.10.067 BindingDB Entry DOI: 10.7270/Q2CN73CD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM50157912 (13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL | Assay Description Inhibitory concentration against Acetylcholinesterase activity | Bioorg Med Chem Lett 15: 353-6 (2004) Article DOI: 10.1016/j.bmcl.2004.10.067 BindingDB Entry DOI: 10.7270/Q2CN73CD | |||||||||||
More data for this Ligand-Target Pair |