BDBM50158023 4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-sulfonyl]-phenylamine::CHEMBL444015
SMILES: Nc1ccc(cc1)S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12
InChI Key: InChIKey=VGOOFUGEHCADCQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50158023 (4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSD | Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50158023 (4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against human cloned 5-hydroxytryptamine 7 receptor stably expressed in CHO cells using [3H]-LSD | Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50158023 (4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against human cloned 5-hydroxytryptamine 1A receptor stably expressed in CHO cells using [3H]-5-HT | Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50158023 (4-[3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-indole-1-su...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptor | Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ | |||||||||||
More data for this Ligand-Target Pair |