BDBM50158038 1-Benzenesulfonyl-5-fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL361189

SMILES: Fc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=NUUVOLYIPWHLCL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50158038 (1-Benzenesulfonyl-5-fluoro-3-(1,2,3,6-tetrahydro-p...) Show SMILES Fc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C19H17FN2O2S/c20-15-6-7-19-17(12-15)18(14-8-10-21-11-9-14)13-22(19)25(23,24)16-4-2-1-3-5-16/h1-8,12-13,21H,9-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSD				Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50158038 (1-Benzenesulfonyl-5-fluoro-3-(1,2,3,6-tetrahydro-p...) Show SMILES Fc1ccc2n(cc(C3=CCNCC3)c2c1)S(=O)(=O)c1ccccc1 |t:8| Show InChI InChI=1S/C19H17FN2O2S/c20-15-6-7-19-17(12-15)18(14-8-10-21-11-9-14)13-22(19)25(23,24)16-4-2-1-3-5-16/h1-8,12-13,21H,9-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells				J Med Chem 57: 7160-81 (2014) Article DOI: 10.1021/jm5003952 BindingDB Entry DOI: 10.7270/Q2X92CZZ
					More data for this Ligand-Target Pair