BDBM50158044 1-(3-Chloro-benzenesulfonyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL359876

SMILES: CN1CCC(=CC1)c1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1

InChI Key: InChIKey=FPRZVIQCJRSZQP-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50158044 (1-(3-Chloro-benzenesulfonyl)-3-(1-methyl-1,2,3,6-t...) Show SMILES CN1CCC(=CC1)c1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 |c:4| Show InChI InChI=1S/C20H19ClN2O2S/c1-22-11-9-15(10-12-22)19-14-23(20-8-3-2-7-18(19)20)26(24,25)17-6-4-5-16(21)13-17/h2-9,13-14H,10-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSD				Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50158044 (1-(3-Chloro-benzenesulfonyl)-3-(1-methyl-1,2,3,6-t...) Show SMILES CN1CCC(=CC1)c1cn(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 |c:4| Show InChI InChI=1S/C20H19ClN2O2S/c1-22-11-9-15(10-12-22)19-14-23(20-8-3-2-7-18(19)20)26(24,25)17-6-4-5-16(21)13-17/h2-9,13-14H,10-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptor				Bioorg Med Chem Lett 15: 379-83 (2004) Article DOI: 10.1016/j.bmcl.2004.10.064 BindingDB Entry DOI: 10.7270/Q20G3JNQ
					More data for this Ligand-Target Pair