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SMILES: FC(F)(F)CCN(Cc1sc(Nc2c(Cl)cc(Cl)cc2Cl)nc1C(F)(F)F)Cc1ccccc1

InChI Key: InChIKey=KRYGUKXOSONLGA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158123   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50158123
PNG
((5-{[Benzyl-(3,3,3-trifluoro-propyl)-amino]-methyl...)
Show SMILES FC(F)(F)CCN(Cc1sc(Nc2c(Cl)cc(Cl)cc2Cl)nc1C(F)(F)F)Cc1ccccc1
Show InChI InChI=1S/C21H16Cl3F6N3S/c22-13-8-14(23)17(15(24)9-13)31-19-32-18(21(28,29)30)16(34-19)11-33(7-6-20(25,26)27)10-12-4-2-1-3-5-12/h1-5,8-9H,6-7,10-11H2,(H,31,32)
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MMDB

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Article
PubMed
 6.10n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibtion of [125I]-Tyr-o-CRF binding to Corticotropin releasing factor receptor 1 expressed in IMR-32 human neuroblastoma cells

Bioorg Med Chem Lett 15: 431-4 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.055
BindingDB Entry DOI: 10.7270/Q2M61JR4
More data for this
Ligand-Target Pair