BDBM50158163 CHEMBL3780277
SMILES: CC1CN(Cc2cccc(c2)C(N)=N)C(=O)N(C1)C1CCN(Cc2ccccc2)CC1
InChI Key: InChIKey=XFCBYZFSKKFRQH-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Trypsin (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor activator/Serine protease hepsin/Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepsin (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor activator (Homo sapiens (Human)) | BDBM50158163 (CHEMBL3780277) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Curated by ChEMBL | Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis | ACS Med Chem Lett 7: 177-81 (2016) BindingDB Entry DOI: 10.7270/Q2Z60QZM | |||||||||||
More data for this Ligand-Target Pair |