BDBM50158240 5-Chloro-1H-indole-2-carboxylic acid {[(2-hydroxy-ethyl)-isobutyl-carbamoyl]-methyl}-amide::CHEMBL361860

SMILES: CC(C)CN(CCO)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=MOBDUICREOHGRU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50158240 (5-Chloro-1H-indole-2-carboxylic acid {[(2-hydroxy-...) Show SMILES CC(C)CN(CCO)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C17H22ClN3O3/c1-11(2)10-21(5-6-22)16(23)9-19-17(24)15-8-12-7-13(18)3-4-14(12)20-15/h3-4,7-8,11,20,22H,5-6,9-10H2,1-2H3,(H,19,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against glycogen phosphorylase				Bioorg Med Chem Lett 15: 459-65 (2004) Article DOI: 10.1016/j.bmcl.2004.10.048 BindingDB Entry DOI: 10.7270/Q26W99K6
					More data for this Ligand-Target Pair