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BDBM50158261 5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl-(2,3-dihydroxy-2-methyl-propyl)-carbamoyl]-methyl}-amide::CHEMBL180985

SMILES: CC(O)(CO)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=ZERIQEVROJRITN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158261   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50158261
PNG
(5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl...)
Show SMILES CC(O)(CO)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C20H26ClN3O4/c1-20(28,12-25)11-24(15-4-2-3-5-15)18(26)10-22-19(27)17-9-13-8-14(21)6-7-16(13)23-17/h6-9,15,23,25,28H,2-5,10-12H2,1H3,(H,22,27)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 83n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Bioorg Med Chem Lett 15: 459-65 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.048
BindingDB Entry DOI: 10.7270/Q26W99K6
More data for this
Ligand-Target Pair