BDBM50158261 5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl-(2,3-dihydroxy-2-methyl-propyl)-carbamoyl]-methyl}-amide::CHEMBL180985

SMILES: CC(O)(CO)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=ZERIQEVROJRITN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50158261 (5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl...) Show SMILES CC(O)(CO)CN(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C20H26ClN3O4/c1-20(28,12-25)11-24(15-4-2-3-5-15)18(26)10-22-19(27)17-9-13-8-14(21)6-7-16(13)23-17/h6-9,15,23,25,28H,2-5,10-12H2,1H3,(H,22,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory concentration against glycogen phosphorylase				Bioorg Med Chem Lett 15: 459-65 (2004) Article DOI: 10.1016/j.bmcl.2004.10.048 BindingDB Entry DOI: 10.7270/Q26W99K6
					More data for this Ligand-Target Pair