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BDBM50158268 5-Chloro-1H-indole-2-carboxylic acid {[furan-2-ylmethyl-(2-hydroxy-ethyl)-carbamoyl]-methyl}-amide::CHEMBL427311

SMILES: OCCN(Cc1ccco1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=LNWSHSVPWJWYDQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158268   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50158268
PNG
(5-Chloro-1H-indole-2-carboxylic acid {[furan-2-ylm...)
Show SMILES OCCN(Cc1ccco1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C18H18ClN3O4/c19-13-3-4-15-12(8-13)9-16(21-15)18(25)20-10-17(24)22(5-6-23)11-14-2-1-7-26-14/h1-4,7-9,21,23H,5-6,10-11H2,(H,20,25)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Bioorg Med Chem Lett 15: 459-65 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.048
BindingDB Entry DOI: 10.7270/Q26W99K6
More data for this
Ligand-Target Pair