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BDBM50158270 5-Chloro-1H-indole-2-carboxylic acid [(methyl-pyridin-3-yl-carbamoyl)-methyl]-amide::CHEMBL181626

SMILES: CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)c1cccnc1

InChI Key: InChIKey=SZQHNTRDOVKERN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158270   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50158270
PNG
(5-Chloro-1H-indole-2-carboxylic acid [(methyl-pyri...)
Show SMILES CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)c1cccnc1
Show InChI InChI=1S/C17H15ClN4O2/c1-22(13-3-2-6-19-9-13)16(23)10-20-17(24)15-8-11-7-12(18)4-5-14(11)21-15/h2-9,21H,10H2,1H3,(H,20,24)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Bioorg Med Chem Lett 15: 459-65 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.048
BindingDB Entry DOI: 10.7270/Q26W99K6
More data for this
Ligand-Target Pair