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BDBM50158307 5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl-(3-hydroxy-1-methyl-propyl)-carbamoyl]-methyl}-amide::CHEMBL178288

SMILES: CC(CCO)N(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=BLWJSOSTWMPKFJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGL)


(Homo sapiens (Human))
BDBM50158307
PNG
(5-Chloro-1H-indole-2-carboxylic acid {[cyclopentyl...)
Show SMILES CC(CCO)N(C1CCCC1)C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C20H26ClN3O3/c1-13(8-9-25)24(16-4-2-3-5-16)19(26)12-22-20(27)18-11-14-10-15(21)6-7-17(14)23-18/h6-7,10-11,13,16,23,25H,2-5,8-9,12H2,1H3,(H,22,27)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 210n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory concentration against glycogen phosphorylase


Bioorg Med Chem Lett 15: 459-65 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.048
BindingDB Entry DOI: 10.7270/Q26W99K6
More data for this
Ligand-Target Pair