BDBM50158337 3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole::CHEMBL374614

SMILES: FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=UDLYEMLMPPYKCH-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50158337 (3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromet...) Show SMILES FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H9Cl2F3N2OS/c20-11-6-7-12(14(21)8-11)17-25-18(27-26-17)15-9-13(10-4-2-1-3-5-10)16(28-15)19(22,23)24/h1-9H	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine 1 phosphate from human S1P4 receptor expressed in CHO cells				J Med Chem 47: 6662-5 (2004) Article DOI: 10.1021/jm0492507 BindingDB Entry DOI: 10.7270/Q2TQ611F
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50158337 (3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromet...) Show SMILES FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H9Cl2F3N2OS/c20-11-6-7-12(14(21)8-11)17-25-18(27-26-17)15-9-13(10-4-2-1-3-5-10)16(28-15)19(22,23)24/h1-9H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine 1 phosphate from human S1P3 receptor expressed in CHO cells				J Med Chem 47: 6662-5 (2004) Article DOI: 10.1021/jm0492507 BindingDB Entry DOI: 10.7270/Q2TQ611F
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human))	BDBM50158337 (3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromet...) Show SMILES FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H9Cl2F3N2OS/c20-11-6-7-12(14(21)8-11)17-25-18(27-26-17)15-9-13(10-4-2-1-3-5-10)16(28-15)19(22,23)24/h1-9H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine 1 phosphate from human S1P2 receptor expressed in CHO cells				J Med Chem 47: 6662-5 (2004) Article DOI: 10.1021/jm0492507 BindingDB Entry DOI: 10.7270/Q2TQ611F
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human))	BDBM50158337 (3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromet...) Show SMILES FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H9Cl2F3N2OS/c20-11-6-7-12(14(21)8-11)17-25-18(27-26-17)15-9-13(10-4-2-1-3-5-10)16(28-15)19(22,23)24/h1-9H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine 1 phosphate from human S1P5 receptor expressed in CHO cells				J Med Chem 47: 6662-5 (2004) Article DOI: 10.1021/jm0492507 BindingDB Entry DOI: 10.7270/Q2TQ611F
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50158337 (3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromet...) Show SMILES FC(F)(F)c1sc(cc1-c1ccccc1)-c1nc(no1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H9Cl2F3N2OS/c20-11-6-7-12(14(21)8-11)17-25-18(27-26-17)15-9-13(10-4-2-1-3-5-10)16(28-15)19(22,23)24/h1-9H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [33P]sphingosine 1 phosphate from human S1P1 receptor expressed in CHO cells				J Med Chem 47: 6662-5 (2004) Article DOI: 10.1021/jm0492507 BindingDB Entry DOI: 10.7270/Q2TQ611F
					More data for this Ligand-Target Pair