BDBM50158493 CHEMBL3787360
SMILES: Nc1ncnc2n(cc(-c3cccc(OCC45CCC(CC4)O5)c3F)c12)[C@@H]1C[C@H](CN2CC[S+]([O-])CC2)C1
InChI Key: InChIKey=VTEJDQKFIBPFFN-ITXHVEOOSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin-like growth factor I receptor (Homo sapiens (Human)) | BDBM50158493 (CHEMBL3787360) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of IGF-1 receptor (unknown origin) in presence of [gamma33P]ATP | Bioorg Med Chem Lett 26: 2057-64 (2016) BindingDB Entry DOI: 10.7270/Q29K4D4J | |||||||||||
More data for this Ligand-Target Pair |