BDBM50158712 3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-thiazolidin-3-yl}-N-[4-(thiazol-2-ylsulfamoyl)-phenyl]-propionamide::CHEMBL180113

SMILES: Cc1ccc(\C=C2/SC(=S)N(CCC(=O)Nc3ccc(cc3)S(=O)(=O)Nc3nccs3)C2=O)cc1

InChI Key: InChIKey=YOYKMQBOLMEHSU-RGEXLXHISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158712 (3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-t...) Show SMILES Cc1ccc(\C=C2/SC(=S)N(CCC(=O)Nc3ccc(cc3)S(=O)(=O)Nc3nccs3)C2=O)cc1 Show InChI InChI=1S/C23H20N4O4S4/c1-15-2-4-16(5-3-15)14-19-21(29)27(23(32)34-19)12-10-20(28)25-17-6-8-18(9-7-17)35(30,31)26-22-24-11-13-33-22/h2-9,11,13-14H,10,12H2,1H3,(H,24,26)(H,25,28)/b19-14-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158712 (3-{4-Oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-t...) Show SMILES Cc1ccc(\C=C2/SC(=S)N(CCC(=O)Nc3ccc(cc3)S(=O)(=O)Nc3nccs3)C2=O)cc1 Show InChI InChI=1S/C23H20N4O4S4/c1-15-2-4-16(5-3-15)14-19-21(29)27(23(32)34-19)12-10-20(28)25-17-6-8-18(9-7-17)35(30,31)26-22-24-11-13-33-22/h2-9,11,13-14H,10,12H2,1H3,(H,24,26)(H,25,28)/b19-14-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair