BDBM50158717 CHEMBL367031::N-(2-Hydroxy-4-nitro-phenyl)-2-{4-oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-thiazolidin-3-yl}-acetamide

SMILES: Cc1ccc(\C=C2/SC(=S)N(CC(=O)Nc3ccc(cc3O)[N+]([O-])=O)C2=O)cc1

InChI Key: InChIKey=JHNYEJDKWJUAJI-PXNMLYILSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158717 (CHEMBL367031 | N-(2-Hydroxy-4-nitro-phenyl)-2-{4-o...) Show SMILES Cc1ccc(\C=C2/SC(=S)N(CC(=O)Nc3ccc(cc3O)[N+]([O-])=O)C2=O)cc1 Show InChI InChI=1S/C19H15N3O5S2/c1-11-2-4-12(5-3-11)8-16-18(25)21(19(28)29-16)10-17(24)20-14-7-6-13(22(26)27)9-15(14)23/h2-9,23H,10H2,1H3,(H,20,24)/b16-8-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158717 (CHEMBL367031 | N-(2-Hydroxy-4-nitro-phenyl)-2-{4-o...) Show SMILES Cc1ccc(\C=C2/SC(=S)N(CC(=O)Nc3ccc(cc3O)[N+]([O-])=O)C2=O)cc1 Show InChI InChI=1S/C19H15N3O5S2/c1-11-2-4-12(5-3-11)8-16-18(25)21(19(28)29-16)10-17(24)20-14-7-6-13(22(26)27)9-15(14)23/h2-9,23H,10H2,1H3,(H,20,24)/b16-8-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair