BDBM50158724 5-[1-(2,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-3-phenyl-2-thioxo-thiazolidin-4-one::CHEMBL367845

SMILES: Oc1ccc(\C=C2/SC(=S)N(C2=O)c2ccccc2)c(O)c1

InChI Key: InChIKey=PTMNLRHJDFCBOR-ZSOIEALJSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158724 (5-[1-(2,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-3-ph...) Show SMILES Oc1ccc(\C=C2/SC(=S)N(C2=O)c2ccccc2)c(O)c1 Show InChI InChI=1S/C16H11NO3S2/c18-12-7-6-10(13(19)9-12)8-14-15(20)17(16(21)22-14)11-4-2-1-3-5-11/h1-9,18-19H/b14-8-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158724 (5-[1-(2,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-3-ph...) Show SMILES Oc1ccc(\C=C2/SC(=S)N(C2=O)c2ccccc2)c(O)c1 Show InChI InChI=1S/C16H11NO3S2/c18-12-7-6-10(13(19)9-12)8-14-15(20)17(16(21)22-14)11-4-2-1-3-5-11/h1-9,18-19H/b14-8-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair