BDBM50158732 5-{5-[(E)-2-Cyano-2-(5-methyl-1H-benzoimidazol-2-yl)-vinyl]-furan-2-yl}-2-hydroxy-benzoic acid::CHEMBL175880

SMILES: Cc1ccc2nc([nH]c2c1)C(=Cc1ccc(o1)-c1ccc(O)c(c1)C(O)=O)C#N

InChI Key: InChIKey=YDVNJBSLEARQPA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158732 (5-{5-[(E)-2-Cyano-2-(5-methyl-1H-benzoimidazol-2-y...) Show SMILES Cc1ccc2nc([nH]c2c1)C(=Cc1ccc(o1)-c1ccc(O)c(c1)C(O)=O)C#N |w:11.13| Show InChI InChI=1S/C22H15N3O4/c1-12-2-5-17-18(8-12)25-21(24-17)14(11-23)9-15-4-7-20(29-15)13-3-6-19(26)16(10-13)22(27)28/h2-10,26H,1H3,(H,24,25)(H,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50158732 (5-{5-[(E)-2-Cyano-2-(5-methyl-1H-benzoimidazol-2-y...) Show SMILES Cc1ccc2nc([nH]c2c1)C(=Cc1ccc(o1)-c1ccc(O)c(c1)C(O)=O)C#N |w:11.13| Show InChI InChI=1S/C22H15N3O4/c1-12-2-5-17-18(8-12)25-21(24-17)14(11-23)9-15-4-7-20(29-15)13-3-6-19(26)16(10-13)22(27)28/h2-10,26H,1H3,(H,24,25)(H,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer)				J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6
					More data for this Ligand-Target Pair