BDBM50158749 CHEMBL367493::N-(2-Hydroxy-5-nitro-phenyl)-2-{4-oxo-2-thioxo-5-[1-p-tolyl-meth-(Z)-ylidene]-thiazolidin-3-yl}-acetamide
SMILES: Cc1ccc(\C=C2/SC(=S)N(CC(=O)Nc3cc(ccc3O)[N+]([O-])=O)C2=O)cc1
InChI Key: InChIKey=YTIOXFDZKUWKOD-PXNMLYILSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50158749 (CHEMBL367493 | N-(2-Hydroxy-5-nitro-phenyl)-2-{4-o...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (Strand Transfer) | J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) | BDBM50158749 (CHEMBL367493 | N-(2-Hydroxy-5-nitro-phenyl)-2-{4-o...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Southern California Curated by ChEMBL | Assay Description Inhibitory concentration against human immuno deficiency virus type 1 integrase (3'-processing) | J Med Chem 48: 111-20 (2005) Article DOI: 10.1021/jm0496077 BindingDB Entry DOI: 10.7270/Q28S4PD6 | |||||||||||
More data for this Ligand-Target Pair |