BDBM50158822 4-[2-(5-Bromo-2-cyano-phenoxy)-phenyl]-2,4-dioxo-butyric acid::CHEMBL446360

SMILES: OC(=O)C(=O)CC(=O)c1ccccc1Oc1cc(Br)ccc1C#N

InChI Key: InChIKey=MZRLVTBCNRYOPE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV))	BDBM50158822 (4-[2-(5-Bromo-2-cyano-phenoxy)-phenyl]-2,4-dioxo-b...) Show SMILES OC(=O)C(=O)CC(=O)c1ccccc1Oc1cc(Br)ccc1C#N Show InChI InChI=1S/C17H10BrNO5/c18-11-6-5-10(9-19)16(7-11)24-15-4-2-1-3-12(15)13(20)8-14(21)17(22)23/h1-7H,8H2,(H,22,23)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibitory concentration against hepatitis C virus polymerase				J Med Chem 48: 1-20 (2005) Article DOI: 10.1021/jm0400101 BindingDB Entry DOI: 10.7270/Q2XP75Q1
					More data for this Ligand-Target Pair