BDBM50159028 1-Benzyl-4-(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperazine::CHEMBL369091

SMILES: C(C1CCc2ccccc2C1)N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=XBTOAGKXNKAIIR-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50159028 (1-Benzyl-4-(1,2,3,4-tetrahydro-naphthalen-2-ylmeth...) Show SMILES C(C1CCc2ccccc2C1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H28N2/c1-2-6-19(7-3-1)17-23-12-14-24(15-13-23)18-20-10-11-21-8-4-5-9-22(21)16-20/h1-9,20H,10-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocine				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50159028 (1-Benzyl-4-(1,2,3,4-tetrahydro-naphthalen-2-ylmeth...) Show SMILES C(C1CCc2ccccc2C1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H28N2/c1-2-6-19(7-3-1)17-23-12-14-24(15-13-23)18-20-10-11-21-8-4-5-9-22(21)16-20/h1-9,20H,10-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidine				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50159028 (1-Benzyl-4-(1,2,3,4-tetrahydro-naphthalen-2-ylmeth...) Show SMILES C(C1CCc2ccccc2C1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H28N2/c1-2-6-19(7-3-1)17-23-12-14-24(15-13-23)18-20-10-11-21-8-4-5-9-22(21)16-20/h1-9,20H,10-18H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant was determined against 5-hydroxytryptamine 1A receptor using 1.2 nM [3H]8-OH-DPAT				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
					More data for this Ligand-Target Pair