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BDBM50159072 2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-N-methyl-N-(2-pyridin-2-yl-ethyl)-acetamide::CHEMBL427317

SMILES: CN(CCc1ccccn1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1

InChI Key: InChIKey=HGYZAKWTGAZJRR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159072   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159072
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES CN(CCc1ccccn1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H19Cl3N4O/c1-29(11-9-18-4-2-3-10-27-18)21(31)13-20-22(15-5-7-16(24)8-6-15)28-23-19(26)12-17(25)14-30(20)23/h2-8,10,12,14H,9,11,13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
530n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159072
PNG
(2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]...)
Show SMILES CN(CCc1ccccn1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H19Cl3N4O/c1-29(11-9-18-4-2-3-10-27-18)21(31)13-20-22(15-5-7-16(24)8-6-15)28-23-19(26)12-17(25)14-30(20)23/h2-8,10,12,14H,9,11,13H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.69E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair