new BindingDB logo
myBDB logout

BDBM50159080 1-{2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-acetyl}-piperidine-3-carboxylic acid ethyl ester::CHEMBL361968

SMILES: CCOC(=O)C1CCCN(C1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1

InChI Key: InChIKey=BGLJZGMDUTWQNZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159080   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159080
PNG
(1-{2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2...)
Show SMILES CCOC(=O)C1CCCN(C1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H22Cl3N3O3/c1-2-32-23(31)15-4-3-9-28(12-15)20(30)11-19-21(14-5-7-16(24)8-6-14)27-22-18(26)10-17(25)13-29(19)22/h5-8,10,13,15H,2-4,9,11-12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
79.8n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159080
PNG
(1-{2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2...)
Show SMILES CCOC(=O)C1CCCN(C1)C(=O)Cc1c(nc2c(Cl)cc(Cl)cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H22Cl3N3O3/c1-2-32-23(31)15-4-3-9-28(12-15)20(30)11-19-21(14-5-7-16(24)8-6-14)27-22-18(26)10-17(25)13-29(19)22/h5-8,10,13,15H,2-4,9,11-12H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.74E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair