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BDBM50159083 2-(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-1-(3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::2-[6,8-Dichloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-1-(3,4-dihydro-1H-isoquinolin-2-yl)-ethanone::CHEMBL369327

SMILES: Clc1cc(Cl)c2nc(c(CC(=O)N3CCc4ccccc4C3)n2c1)-c1ccccc1

InChI Key: InChIKey=SRFABXYYYLFIHZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159083   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159083
PNG
(2-(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-y...)
Show SMILES Clc1cc(Cl)c2nc(c(CC(=O)N3CCc4ccccc4C3)n2c1)-c1ccccc1
Show InChI InChI=1S/C24H19Cl2N3O/c25-19-12-20(26)24-27-23(17-7-2-1-3-8-17)21(29(24)15-19)13-22(30)28-11-10-16-6-4-5-9-18(16)14-28/h1-9,12,15H,10-11,13-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
23.6n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat cerebral cortex


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))
BDBM50159083
PNG
(2-(6,8-Dichloro-2-phenyl-imidazo[1,2-a]pyridin-3-y...)
Show SMILES Clc1cc(Cl)c2nc(c(CC(=O)N3CCc4ccccc4C3)n2c1)-c1ccccc1
Show InChI InChI=1S/C24H19Cl2N3O/c25-19-12-20(26)24-27-23(17-7-2-1-3-8-17)21(29(24)15-19)13-22(30)28-11-10-16-6-4-5-9-18(16)14-28/h1-9,12,15H,10-11,13-14H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
164n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]-PK11195 from peripheral benzodiazepine receptor of rat ovary


J Med Chem 48: 292-305 (2005)


Article DOI: 10.1021/jm049610q
BindingDB Entry DOI: 10.7270/Q2RR1XQ0
More data for this
Ligand-Target Pair