BDBM50159111 (R)-2-Quinolin-2-yl-octahydro-pyrido[1,2-a]pyrazine::CHEMBL178609

SMILES: C1CCN2CCN(C[C@H]2C1)c1ccc2ccccc2n1

InChI Key: InChIKey=XSEBHCNVSJIJOI-OAHLLOKOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159111 ((R)-2-Quinolin-2-yl-octahydro-pyrido[1,2-a]pyrazin...) Show SMILES C1CCN2CCN(C[C@H]2C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C17H21N3/c1-2-7-16-14(5-1)8-9-17(18-16)20-12-11-19-10-4-3-6-15(19)13-20/h1-2,5,7-9,15H,3-4,6,10-13H2/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair