BDBM50159115 CHEMBL179306::[2-(4-Cyclopropyl-piperazin-1-yl)-quinolin-6-yl]-(4-fluoro-phenyl)-methanone

SMILES: Fc1ccc(cc1)C(=O)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=WUQWVKYUTITJHA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159115 (CHEMBL179306 | [2-(4-Cyclopropyl-piperazin-1-yl)-q...) Show SMILES Fc1ccc(cc1)C(=O)c1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C23H22FN3O/c24-19-5-1-16(2-6-19)23(28)18-3-9-21-17(15-18)4-10-22(25-21)27-13-11-26(12-14-27)20-7-8-20/h1-6,9-10,15,20H,7-8,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair