BDBM50159118 6-Chloro-2-(4-cyclopropyl-piperazin-1-yl)-quinoline::CHEMBL368701

SMILES: Clc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=UHKZBUYMQGXDPY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159118 (6-Chloro-2-(4-cyclopropyl-piperazin-1-yl)-quinolin...) Show SMILES Clc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C16H18ClN3/c17-13-2-5-15-12(11-13)1-6-16(18-15)20-9-7-19(8-10-20)14-3-4-14/h1-2,5-6,11,14H,3-4,7-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair