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BDBM50159121 2-(4-Cyclopropyl-piperazin-1-yl)-quinoline-6-carbonitrile::CHEMBL179672

SMILES: N#Cc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=XDRABJSEVOSBLL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM50159121
PNG
(2-(4-Cyclopropyl-piperazin-1-yl)-quinoline-6-carbo...)
Show SMILES N#Cc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1
Show InChI InChI=1S/C17H18N4/c18-12-13-1-5-16-14(11-13)2-6-17(19-16)21-9-7-20(8-10-21)15-3-4-15/h1-2,5-6,11,15H,3-4,7-10H2
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PC sid
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Article
PubMed
4.80n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Antagonist potency against human H3 receptor in GTPgamma[S]-Assay


J Med Chem 48: 306-11 (2005)


Article DOI: 10.1021/jm040873u
BindingDB Entry DOI: 10.7270/Q2N0161T
More data for this
Ligand-Target Pair