BDBM50159122 2-(4-Cyclopropyl-piperazin-1-yl)-6-methoxy-quinoline::CHEMBL179624

SMILES: COc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1

InChI Key: InChIKey=KLICDCLQKNALRB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159122 (2-(4-Cyclopropyl-piperazin-1-yl)-6-methoxy-quinoli...) Show SMILES COc1ccc2nc(ccc2c1)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H21N3O/c1-21-15-5-6-16-13(12-15)2-7-17(18-16)20-10-8-19(9-11-20)14-3-4-14/h2,5-7,12,14H,3-4,8-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human H3 receptor in GTPgamma[S]-Assay				J Med Chem 48: 306-11 (2005) Article DOI: 10.1021/jm040873u BindingDB Entry DOI: 10.7270/Q2N0161T
					More data for this Ligand-Target Pair