null

SMILES: COC1CN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccc(OC)cc3)cc2)C1

InChI Key: InChIKey=JHHMLOGRXQPDON-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50159143 (CHEMBL3786350) Show SMILES COC1CN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccc(OC)cc3)cc2)C1 Show InChI InChI=1S/C24H26N4O5/c1-30-18-9-5-17(6-10-18)22-25-26-23(33-22)24(29)28-14-21(15-28)32-19-7-3-16(4-8-19)11-27-12-20(13-27)31-2/h3-10,20-21H,11-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG by IonWork assay				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50159143 (CHEMBL3786350) Show SMILES COC1CN(Cc2ccc(OC3CN(C3)C(=O)c3nnc(o3)-c3ccc(OC)cc3)cc2)C1 Show InChI InChI=1S/C24H26N4O5/c1-30-18-9-5-17(6-10-18)22-25-26-23(33-22)24(29)28-14-21(15-28)32-19-7-3-16(4-8-19)11-27-12-20(13-27)31-2/h3-10,20-21H,11-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair