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SMILES: Clc1ccc(cc1Cl)S(=O)(=O)Nc1ccc2[nH]cc(CC3CCCN3)c2c1

InChI Key: InChIKey=PEPNLUGXUMBWDE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159198   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50159198
PNG
(3,4-Dichloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-i...)
Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)Nc1ccc2[nH]cc(CC3CCCN3)c2c1
Show InChI InChI=1S/C19H19Cl2N3O2S/c20-17-5-4-15(10-18(17)21)27(25,26)24-14-3-6-19-16(9-14)12(11-23-19)8-13-2-1-7-22-13/h3-6,9-11,13,22-24H,1-2,7-8H2
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Article
PubMed
 3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cells

J Med Chem 48: 353-6 (2005)


Article DOI: 10.1021/jm049243i
BindingDB Entry DOI: 10.7270/Q27W6D00
More data for this
Ligand-Target Pair