BDBM50159199 4-Isopropyl-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide

SMILES: CC(C)c1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]cc(CC3CCCN3)c2c1

InChI Key: InChIKey=KTTVLQCVCOFIAK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50159199 (4-Isopropyl-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-in...) Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]cc(CC3CCCN3)c2c1 Show InChI InChI=1S/C22H27N3O2S/c1-15(2)16-5-8-20(9-6-16)28(26,27)25-19-7-10-22-21(13-19)17(14-24-22)12-18-4-3-11-23-18/h5-10,13-15,18,23-25H,3-4,11-12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cells				J Med Chem 48: 353-6 (2005) Article DOI: 10.1021/jm049243i BindingDB Entry DOI: 10.7270/Q27W6D00
					More data for this Ligand-Target Pair