null

SMILES: COc1ccc(cc1)-c1nnc(o1)C(=O)N1CCC(CC1)Oc1ccc(CN2CC(O)C(C)(C)C2)cc1

InChI Key: InChIKey=DATKXEGBFDTYBY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50159336 (CHEMBL3787462) Show SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CCC(CC1)Oc1ccc(CN2CC(O)C(C)(C)C2)cc1 Show InChI InChI=1S/C28H34N4O5/c1-28(2)18-31(17-24(28)33)16-19-4-8-22(9-5-19)36-23-12-14-32(15-13-23)27(34)26-30-29-25(37-26)20-6-10-21(35-3)11-7-20/h4-11,23-24,33H,12-18H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50159336 (CHEMBL3787462) Show SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CCC(CC1)Oc1ccc(CN2CC(O)C(C)(C)C2)cc1 Show InChI InChI=1S/C28H34N4O5/c1-28(2)18-31(17-24(28)33)16-19-4-8-22(9-5-19)36-23-12-14-32(15-13-23)27(34)26-30-29-25(37-26)20-6-10-21(35-3)11-7-20/h4-11,23-24,33H,12-18H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG by IonWork assay				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50159336 (CHEMBL3787462) Show SMILES COc1ccc(cc1)-c1nnc(o1)C(=O)N1CCC(CC1)Oc1ccc(CN2CC(O)C(C)(C)C2)cc1 Show InChI InChI=1S/C28H34N4O5/c1-28(2)18-31(17-24(28)33)16-19-4-8-22(9-5-19)36-23-12-14-32(15-13-23)27(34)26-30-29-25(37-26)20-6-10-21(35-3)11-7-20/h4-11,23-24,33H,12-18H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [125I]Tyr13-MCH from human MCHR1 expressed in CHO cell membranes after 60 mins by microbeta scintillation counting analysis				J Med Chem 59: 2497-511 (2016) BindingDB Entry DOI: 10.7270/Q23R0VSS
					More data for this Ligand-Target Pair