BDBM50159451 CHEMBL216992::Des-AA1,2,5,12,13-[D-Trp8]SRIF
SMILES: C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O
InChI Key: InChIKey=ANCUAJMQRRZZNC-JFMJRBFYSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50159451 (CHEMBL216992 | Des-AA1,2,5,12,13-[D-Trp8]SRIF) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 5 | J Med Chem 48: 515-22 (2005) Article DOI: 10.1021/jm049519m BindingDB Entry DOI: 10.7270/Q2QV3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50159451 (CHEMBL216992 | Des-AA1,2,5,12,13-[D-Trp8]SRIF) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 1 | J Med Chem 48: 515-22 (2005) Article DOI: 10.1021/jm049519m BindingDB Entry DOI: 10.7270/Q2QV3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50159451 (CHEMBL216992 | Des-AA1,2,5,12,13-[D-Trp8]SRIF) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 4 | J Med Chem 48: 515-22 (2005) Article DOI: 10.1021/jm049519m BindingDB Entry DOI: 10.7270/Q2QV3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50159451 (CHEMBL216992 | Des-AA1,2,5,12,13-[D-Trp8]SRIF) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 2 | J Med Chem 48: 515-22 (2005) Article DOI: 10.1021/jm049519m BindingDB Entry DOI: 10.7270/Q2QV3N9S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50159451 (CHEMBL216992 | Des-AA1,2,5,12,13-[D-Trp8]SRIF) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Salk Institute Curated by ChEMBL | Assay Description Inhibition of 125I-[Leu8,D-Trp22,Tyr25]SRIF-28 binding to human somatostatin receptor type 3 | J Med Chem 48: 515-22 (2005) Article DOI: 10.1021/jm049519m BindingDB Entry DOI: 10.7270/Q2QV3N9S | |||||||||||
More data for this Ligand-Target Pair |