BDBM50159533 CHEMBL3786653

SMILES: COc1c(NC(=O)C(=O)c2ccc(OCCNC(=O)CN)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=JHNZFRHHODDBIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159533   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Scavenger receptor class B member 1 (Homo sapiens (Human))	BDBM50159533 (CHEMBL3786653) Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCNC(=O)CN)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C Show InChI InChI=1S/C28H34N4O7S/c1-28(2,3)17-14-21(26(38-4)22(15-17)32-40(5,36)37)31-27(35)25(34)20-10-11-23(19-9-7-6-8-18(19)20)39-13-12-30-24(33)16-29/h6-11,14-15,32H,12-13,16,29H2,1-5H3,(H,30,33)(H,31,35)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...				Bioorg Med Chem Lett 26: 1901-4 (2016) BindingDB Entry DOI: 10.7270/Q22R3TJ2
					More data for this Ligand-Target Pair