BDBM50159545 CHEMBL3785828

SMILES: COc1c(NC(=O)C(=O)c2ccc(OCCCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=LAAJOJSDMSEZAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Scavenger receptor class B member 1 (Homo sapiens (Human))	BDBM50159545 (CHEMBL3785828) Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C Show InChI InChI=1S/C32H41N3O7S/c1-32(2,3)22-20-26(30(40-4)27(21-22)34-43(5,38)39)33-31(37)29(36)25-12-13-28(24-11-7-6-10-23(24)25)42-17-9-8-14-35-15-18-41-19-16-35/h6-7,10-13,20-21,34H,8-9,14-19H2,1-5H3,(H,33,37)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...				Bioorg Med Chem Lett 26: 1901-4 (2016) BindingDB Entry DOI: 10.7270/Q22R3TJ2
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