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SMILES: COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(=O)(=O)CCCN(CCO)CCO)C(C)(C)C

InChI Key: InChIKey=OFCBUOPABBUCIE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159550   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))		BDBM50159550
PNG
(CHEMBL3785336)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(=O)(=O)CCCN(CCO)CCO)C(C)(C)C
Show InChI InChI=1S/C36H50N4O9S/c1-36(2,3)26-24-30(34(47-4)31(25-26)38-50(45,46)23-7-12-39(13-18-41)14-19-42)37-35(44)33(43)29-10-11-32(28-9-6-5-8-27(28)29)49-22-17-40-15-20-48-21-16-40/h5-6,8-11,24-25,38,41-42H,7,12-23H2,1-4H3,(H,37,44)
KEGG

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Similars
Article
PubMed
n/an/a 40n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...

Bioorg Med Chem Lett 26: 1901-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.025
BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair