BDBM50159556 CHEMBL3785219

SMILES: COc1c(NC(=O)C(=O)c2ccc(OCCN(CCO)CCO)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key: InChIKey=QBISNYGDFHPMOY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Scavenger receptor class B member 1 (Homo sapiens (Human))	BDBM50159556 (CHEMBL3785219) Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN(CCO)CCO)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C Show InChI InChI=1S/C30H39N3O8S/c1-30(2,3)20-18-24(28(40-4)25(19-20)32-42(5,38)39)31-29(37)27(36)23-10-11-26(22-9-7-6-8-21(22)23)41-17-14-33(12-15-34)13-16-35/h6-11,18-19,32,34-35H,12-17H2,1-5H3,(H,31,37)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...				Bioorg Med Chem Lett 26: 1901-4 (2016) BindingDB Entry DOI: 10.7270/Q22R3TJ2
					More data for this Ligand-Target Pair