BDBM50160094 2-(3,4-Difluoro-benzyloxy)-6-(2,4-difluoro-phenyl)-5-(4-fluoro-phenyl)-nicotinonitrile::CHEMBL362215
SMILES: Fc1ccc(cc1)-c1cc(C#N)c(OCc2ccc(F)c(F)c2)nc1-c1ccc(F)cc1F
InChI Key: InChIKey=PVZXZOAWQQOGED-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50160094 (2-(3,4-Difluoro-benzyloxy)-6-(2,4-difluoro-phenyl)...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibitory concentration tested against human Cannabinoid receptor 1 (hCB1) | Bioorg Med Chem Lett 15: 645-51 (2005) Article DOI: 10.1016/j.bmcl.2004.11.031 BindingDB Entry DOI: 10.7270/Q2X929SW | |||||||||||
More data for this Ligand-Target Pair |