BDBM50160160 (S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-9,11-dioxa-6-aza-benzo[fg]cyclopenta[b]anthracene::CHEMBL179440

SMILES: COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23

InChI Key: InChIKey=WSVWKHTVFGTTKJ-AWEZNQCLSA-N

Data: 39 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 50160160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Prazosin from human adrenergic alpha1A receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]GR127543 from human 5HT1D receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT7 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]GR127543 from human 5HT1B receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Clonidine from human adrenergic Alpha-2C receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Citalopram from human SERT				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	252	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Clonidine from human adrenergic alpha2B receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	262	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D4 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Binding affinity to human adrenergic Alpha-1D receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +:inactive				Bioorg Med Chem Lett 15: 657-64 (2005) Article DOI: 10.1016/j.bmcl.2004.11.032 BindingDB Entry DOI: 10.7270/Q2SN08GW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	543	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT2B receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	672	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Tiotidine from human histamine H2 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	832	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Ketanserin from human 5HT2A receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	895	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]SCH233930 from human dopamine D1 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Mesulergine from human 5HT2C receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Prazosin from human adrenergic Alpha-1B receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Clonidine from human adrenergic alpha2A receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT5A receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]SCH233930 from human dopamine D5 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human MOR				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [125I]Iodopindolol from human adrenergic beta-1 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]DADLE from human DOR				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M4 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M3 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M2 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]QNB from human muscarinic M1 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Histamine from human histamine H4 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]alpha-methylhistamine from human histamine H3 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Pyrilamine from human histamine H1 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from human KOR				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]Nisoxetine from human NET				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [125I]Iodopindolol from human adrenergic beta2 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]WIN-35428 from human DAT				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [125I]Iodopindolol from human adrenergic beta3 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5HT1E receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50160160 ((S)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-...) Show SMILES COc1cc2CCN(C)[C@H]3Cc4cc5OCOc5cc4-c(c1OC)c23 Show InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17(22-2)20(23-3)19-13-9-16-15(24-10-25-16)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hunter College and the Graduate Center of the City University of New York Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from human 5HT3 receptor				Bioorg Med Chem Lett 20: 628-31 (2010) Article DOI: 10.1016/j.bmcl.2009.11.053 BindingDB Entry DOI: 10.7270/Q2C53MT3
					More data for this Ligand-Target Pair