BDBM50160288 CHEMBL3787437

SMILES: Fc1ccc(cc1)[C@@H]1[C@H](N(C2CCNCC2)C1=O)c1ccc2OCOc2c1

InChI Key: InChIKey=QPVQOPSMQFJCMD-WOJBJXKFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50160288 (CHEMBL3787437) Show SMILES Fc1ccc(cc1)[C@@H]1[C@H](N(C2CCNCC2)C1=O)c1ccc2OCOc2c1 |r| Show InChI InChI=1S/C21H21FN2O3/c22-15-4-1-13(2-5-15)19-20(14-3-6-17-18(11-14)27-12-26-17)24(21(19)25)16-7-9-23-10-8-16/h1-6,11,16,19-20,23H,7-10,12H2/t19-,20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His6-tagged human MAGL expressed in Escherichia coli using 2-arachidonoyl-[3H]-glycerol as substrate incubated f...				J Med Chem 59: 2612-32 (2016) BindingDB Entry DOI: 10.7270/Q21R6SC7
					More data for this Ligand-Target Pair