BDBM50160566 CHEMBL3786255

SMILES: CC(N1C(C(=O)NCc2ccccc2)c2ccccc2C1=O)c1ccccc1

InChI Key: InChIKey=PULWYSDHOXHDQV-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50160566 (CHEMBL3786255) Show SMILES CC(N1C(C(=O)NCc2ccccc2)c2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c1-17(19-12-6-3-7-13-19)26-22(20-14-8-9-15-21(20)24(26)28)23(27)25-16-18-10-4-2-5-11-18/h2-15,17,22H,16H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160566 (CHEMBL3786255) Show SMILES CC(N1C(C(=O)NCc2ccccc2)c2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c1-17(19-12-6-3-7-13-19)26-22(20-14-8-9-15-21(20)24(26)28)23(27)25-16-18-10-4-2-5-11-18/h2-15,17,22H,16H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160566 (CHEMBL3786255) Show SMILES CC(N1C(C(=O)NCc2ccccc2)c2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C24H22N2O2/c1-17(19-12-6-3-7-13-19)26-22(20-14-8-9-15-21(20)24(26)28)23(27)25-16-18-10-4-2-5-11-18/h2-15,17,22H,16H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by Rb-flux assay				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair