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SMILES: COc1cccc(c1)-c1cccc(c1)C#Cc1cccc(C)n1

InChI Key: InChIKey=BTANQBCKRWEXAU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160630 (2-(3''-Methoxy-biphenyl-3-ylethynyl)-6-methyl-pyri...) Show SMILES COc1cccc(c1)-c1cccc(c1)C#Cc1cccc(C)n1 Show InChI InChI=1S/C21H17NO/c1-16-6-3-10-20(22-16)13-12-17-7-4-8-18(14-17)19-9-5-11-21(15-19)23-2/h3-11,14-15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160630 (2-(3''-Methoxy-biphenyl-3-ylethynyl)-6-methyl-pyri...) Show SMILES COc1cccc(c1)-c1cccc(c1)C#Cc1cccc(C)n1 Show InChI InChI=1S/C21H17NO/c1-16-6-3-10-20(22-16)13-12-17-7-4-8-18(14-17)19-9-5-11-21(15-19)23-2/h3-11,14-15H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	493	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
					More data for this Ligand-Target Pair