null

SMILES: Cc1cccc(n1)C#Cc1cncc(c1)-c1ccccc1

InChI Key: InChIKey=NYCKBHBDURYRAF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160633 (2-methyl-6-[(5-phenylpyridin-3-yl)ethynyl]pyridine...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C19H14N2/c1-15-6-5-9-19(21-15)11-10-16-12-18(14-20-13-16)17-7-3-2-4-8-17/h2-9,12-14H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vitro binding affinity of compound towards rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50160633 (2-methyl-6-[(5-phenylpyridin-3-yl)ethynyl]pyridine...) Show SMILES Cc1cccc(n1)C#Cc1cncc(c1)-c1ccccc1 Show InChI InChI=1S/C19H14N2/c1-15-6-5-9-19(21-15)11-10-16-12-18(14-20-13-16)17-7-3-2-4-8-17/h2-9,12-14H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Concentration required for 50% growth inhibition of rat metabotropic glutamate receptor 5 was determined using inositol phosphate hydrolysis assay				Bioorg Med Chem Lett 15: 945-9 (2005) Article DOI: 10.1016/j.bmcl.2004.12.047 BindingDB Entry DOI: 10.7270/Q2QN6681
					More data for this Ligand-Target Pair