BDBM50160704 CHEMBL3785486

SMILES: CCCCNC(=O)C1N(CC(C)c2ccc(Cl)cc2)C(=O)c2ccccc12

InChI Key: InChIKey=WJOTUGKTXINIMV-HNNXBMFYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50160704 (CHEMBL3785486) Show SMILES CCCCNC(=O)C1N(CC(C)c2ccc(Cl)cc2)C(=O)c2ccccc12 Show InChI InChI=1S/C21H27Cl2N7O3/c1-29-17(11-16(28-29)13-3-2-4-14(22)18(13)23)12-6-9-30(10-7-12)21(33)26-8-5-15(19(31)32)27-20(24)25/h2-4,11-12,15H,5-10H2,1H3,(H,26,33)(H,31,32)(H4,24,25,27)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160704 (CHEMBL3785486) Show SMILES CCCCNC(=O)C1N(CC(C)c2ccc(Cl)cc2)C(=O)c2ccccc12 Show InChI InChI=1S/C21H27Cl2N7O3/c1-29-17(11-16(28-29)13-3-2-4-14(22)18(13)23)12-6-9-30(10-7-12)21(33)26-8-5-15(19(31)32)27-20(24)25/h2-4,11-12,15H,5-10H2,1H3,(H,26,33)(H,31,32)(H4,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by QPatch-clamp method				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50160704 (CHEMBL3785486) Show SMILES CCCCNC(=O)C1N(CC(C)c2ccc(Cl)cc2)C(=O)c2ccccc12 Show InChI InChI=1S/C21H27Cl2N7O3/c1-29-17(11-16(28-29)13-3-2-4-14(22)18(13)23)12-6-9-30(10-7-12)21(33)26-8-5-15(19(31)32)27-20(24)25/h2-4,11-12,15H,5-10H2,1H3,(H,26,33)(H,31,32)(H4,24,25,27)/t15-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel by Rb-flux assay				Bioorg Med Chem Lett 26: 2023-9 (2016) BindingDB Entry DOI: 10.7270/Q2D220HH
					More data for this Ligand-Target Pair