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SMILES: COc1cc(O)c(c2CCc3cc(O)ccc3-c12)-c1c(O)cc(OC)c2c1ccc1cc(O)ccc21

InChI Key: InChIKey=LCCDZCVHGDFKNQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160798   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50160798
PNG
(4,4''-Dimethoxy-9,10-dihydro-[1,1'']biphenanthreny...)
Show SMILES COc1cc(O)c(c2CCc3cc(O)ccc3-c12)-c1c(O)cc(OC)c2c1ccc1cc(O)ccc21 |(-6.98,.32,;-5.62,1.08,;-4.28,.3,;-4.31,-1.24,;-2.97,-2.02,;-2.97,-3.57,;-1.63,-1.27,;-1.63,.27,;-.27,1.03,;-.3,2.58,;-1.61,3.35,;-1.61,4.92,;-2.95,5.69,;-2.97,7.24,;-4.28,4.9,;-4.28,3.35,;-2.95,2.6,;-2.95,1.06,;-.3,-2.05,;-.32,-3.6,;-1.68,-4.35,;1.01,-4.37,;2.35,-3.61,;3.69,-4.39,;5.03,-3.62,;2.35,-2.05,;1.02,-1.27,;1.04,.26,;2.38,1.02,;3.69,.23,;5.03,.99,;6.34,.21,;7.69,.98,;6.34,-1.32,;5,-2.07,;3.69,-1.3,)|
Show InChI InChI=1S/C30H24O6/c1-35-25-13-23(33)29(21-7-3-15-11-17(31)5-9-19(15)27(21)25)30-22-8-4-16-12-18(32)6-10-20(16)28(22)26(36-2)14-24(30)34/h3,5-7,9-14,31-34H,4,8H2,1-2H3
UniProtKB/SwissProt

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KEGG
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization interacting at the colchicine binding site.

Bioorg Med Chem Lett 15: 1051-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.026
BindingDB Entry DOI: 10.7270/Q22Z151S
More data for this
Ligand-Target Pair