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SMILES: COc1cc(O)cc(CCc2cccc(O)c2)c1Cc1ccc(O)cc1

InChI Key: InChIKey=GSRRYHALFWAEMW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160801   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50160801
PNG
(4-(4-Hydroxy-benzyl)-3-[2-(3-hydroxy-phenyl)-ethyl...)
Show SMILES COc1cc(O)cc(CCc2cccc(O)c2)c1Cc1ccc(O)cc1
Show InChI InChI=1S/C22H22O4/c1-26-22-14-20(25)13-17(8-5-15-3-2-4-19(24)11-15)21(22)12-16-6-9-18(23)10-7-16/h2-4,6-7,9-11,13-14,23-25H,5,8,12H2,1H3
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PC sid
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Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization interacting at the colchicine binding site.

Bioorg Med Chem Lett 15: 1051-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.026
BindingDB Entry DOI: 10.7270/Q22Z151S
More data for this
Ligand-Target Pair