BDBM50160803 4,4''-Dimethoxy-9,10,9'',10''-tetrahydro-[1,3'']biphenanthrenyl-2,7,2'',7''-tetraol::CHEMBL185178

SMILES: COc1cc(O)c(c2CCc3cc(O)ccc3-c12)-c1c(O)cc2CCc3cc(O)ccc3-c2c1OC

InChI Key: InChIKey=SRKMCQJMXFPIDU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta tubulin (Leishmania donovani)	BDBM50160803 (4,4''-Dimethoxy-9,10,9'',10''-tetrahydro-[1,3'']bi...) Show SMILES COc1cc(O)c(c2CCc3cc(O)ccc3-c12)-c1c(O)cc2CCc3cc(O)ccc3-c2c1OC |(-6.97,.26,;-5.64,1.03,;-4.31,.27,;-4.31,-1.28,;-2.98,-2.05,;-2.98,-3.58,;-1.65,-1.28,;-1.65,.26,;-.32,1.03,;-.3,2.56,;-1.63,3.33,;-1.6,4.85,;-2.93,5.65,;-2.93,7.18,;-4.29,4.89,;-4.31,3.35,;-2.98,2.57,;-2.98,1.04,;-.32,-2.05,;-.32,-3.59,;-1.65,-4.36,;1.01,-4.36,;2.34,-3.59,;3.67,-4.36,;5.02,-3.59,;5.02,-2.05,;6.38,-1.27,;6.38,.28,;7.73,1.05,;5.02,1.07,;3.69,.3,;3.69,-1.26,;2.34,-2.05,;1.01,-1.27,;1.01,.26,;2.34,1.03,)| Show InChI InChI=1S/C30H26O6/c1-35-25-14-24(34)28(22-8-5-16-12-19(32)7-10-21(16)27(22)25)29-23(33)13-17-4-3-15-11-18(31)6-9-20(15)26(17)30(29)36-2/h6-7,9-14,31-34H,3-5,8H2,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization interacting at the colchicine binding site.				Bioorg Med Chem Lett 15: 1051-4 (2005) Article DOI: 10.1016/j.bmcl.2004.12.026 BindingDB Entry DOI: 10.7270/Q22Z151S
					More data for this Ligand-Target Pair