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SMILES: COc1cc(O)c(Cc2ccc(O)cc2)c2ccc3c(OC)c(O)ccc3c12

InChI Key: InChIKey=FTRCSQQUXKTUOD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160805   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain [1-43]


(Leishmania donovani)		BDBM50160805
PNG
(1-(4-Hydroxy-benzyl)-4,8-dimethoxy-phenanthrene-2,...)
Show SMILES COc1cc(O)c(Cc2ccc(O)cc2)c2ccc3c(OC)c(O)ccc3c12
Show InChI InChI=1S/C23H20O5/c1-27-21-12-20(26)18(11-13-3-5-14(24)6-4-13)16-7-8-17-15(22(16)21)9-10-19(25)23(17)28-2/h3-10,12,24-26H,11H2,1-2H3
UniProtKB/SwissProt

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Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization interacting at the colchicine binding site.

Bioorg Med Chem Lett 15: 1051-4 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.026
BindingDB Entry DOI: 10.7270/Q22Z151S
More data for this
Ligand-Target Pair